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Integrated rate equation for association

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1 month 1 week ago #1 by Drug discovery
Integrated rate equation for association was created by Drug discovery
I have been trying to understand how we can get the first order integrated equation from the differential rate equation to no avail

I have attached a screenshot. It be great if someone can show the actual steps to ge to the final integrated equation

 
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    1 month 6 days ago #2 by Arnoud
    Replied by Arnoud on topic Integrated rate equation for association
    I don't know much about integrating but in short this is it.



    The [A] in your formule is C since it is constant in flow based systems.

    Arnoud
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    1 month 6 days ago #3 by Drug discovery
    Replied by Drug discovery on topic Integrated rate equation for association
    Thank you Arnoud. I got the steps before and after integration but not the actual integration step.

    I was keen to how the variables were separated from the previous step and the subsuequent integration to end up with Ka.C.Rmax / (kaC+Kd)x(1-e*(kaC+Kd)t Just couldn't figure.. yet

    Thank you as always for the quick repsonse and amazing contirbution!!

    cheers

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