Biacore sensor chips
In the Biacore SPR instruments a wide range of sensor surfaces can be used. The actual sensor surface is shielded within a protective sheet. The surfaces range from plain gold to several types of carboxylated dextran matrices and specialized surfaces such as protein G, NTA or streptavidin. In addition, lipophilic surface are also available.
| Chip name | Dextran | Modification | Application |
|---|---|---|---|
| AU | none | none | user defined surface chemistry |
| CAP | 100 nM | oligopeptide | oligopeptide mediated capture of biotin |
| C1 | none | 100% carboxylation | phage binding |
| CM3 | 30 nm | 100% carboxylation | cell extracts / serum and membranes |
| CM4 | 100 nm | 30% carboxylation | cell extracts / serum and membranes |
| CM5 | 100 nm | 100% carboxylation | general |
| CM7 | 100 nm | 100% carboxylation | high density CM-dextran - high capacity |
| HPA | none | hydrophobic | lipid capturing |
| L1 | 100 nm | lipophilic substances | bilayers to mimic membranes |
| NTA | 100 nm | NTA | capturing poly HIS-groups |
| SA | 100 nm | streptavidin | capturing of biotin |
| SIA | none | none | surface interaction analysis in material science |