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Off topic, Protein characterization and binding job opportunity in MA, USA
- yanfengzhou
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3 years 4 months ago #1
by yanfengzhou
Off topic, Protein characterization and binding job opportunity in MA, USA was created by yanfengzhou
Hi,
Sorry for the off topic post. If anyone is looking for a job around Boston area in US, please check the link below.
www.linkedin.com/jobs/view/2662640332/?r...RPGWslMQWMgEOQ%3D%3D
Who we are
Seismic Therapeutic is a VC-backed biotechnology startup focused on the intersection of structure, protein engineering, machine learning and immunology founded by Tim Springer, Jeff Ravetch, Debora Marks and Alan Crane.
What we offer you
As a member of our new and quickly growing company, you’ll help us shape Seismic from the very beginning into a startup that not only takes its scientific mission seriously but also provides a positive and supportive workplace environment and culture. Seismic will have the opportunity to benefit from the insight, diversity, and talent that you’ll bring. Together, we’ll help bring therapeutics to the patients who need them most.
Our mission
Seismic is determined to help patients in need, starting with novel approaches to protein engineering, machine learning and immunology, and ending with clinic-ready drugs. At our core, our focus is on phenomenal science, meritocracy, a superstar team, supportive culture, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality – all we need is you! Success will enable treatment for millions of patients with currently incurable, often disabling and deadly diseases, and we invite you to become a part of that.
Where?
Seismic is located in the dynamic biotech community in Watertown, alongside other new companies that are turning ideas into reality and changing the biotech and medical scenes for the better. We are thrilled to expand our Team with hardworking, highly qualified, highly motivated individuals to join us in our lab space.
Available position
Scientist/Senior Scientist, Biochemistry and protein interactions
General role: In coordination with scientific leadership, you would play a central role in designing and implementing Seismic’s pipeline, with particular focus on processes occurring during biotherapeutic candidate generation, screening and analysis. This role will involve exploring customized solutions in the field of protein-protein interactions, followed by detailed qualitative and quantitative sample analysis, leading into high-throughput screening and characterization techniques. Successfully meeting these challenges will require not only a broad range of protein biochemistry skills, independent thinking, and an aptitude for troubleshooting, but also a strong, creative drive to develop new assays as the need arises.
Your work in this role would be in collaboration with scientists and computational experts throughout Seismic, learning and contributing to many aspects of our pipeline, including the iterative design and production of biotherapeutics. You would be responsible for understanding project goals and for creatively optimizing solutions to ensure their success. Over time you would take on additional responsibilities and contribute to new projects.
Responsibilities:
● Design and implement protocols for characterizing protein-protein interactions.
● Design and optimize qualitative and quantitative biophysical and biochemical studies of biotherapeutic molecules, including assay development and protein QC.
● Share recommendations and insight for pipeline improvement toward higher-throughput and efficiency
● Collaborate with a diverse team of wet-lab scientists, protein engineers, and computational scientists
● Maintain an in depth understanding of the biochemistry, molecular structure and wider role of each candidate through critical analysis of the literature.
Basic qualifications:
● PhD in chemistry, biology, biochemistry, biomedical engineering, or related field
● 5+ years hands-on wet lab experience, including at least two of the following:
o Strong expertise in characterizing protein-protein interaction using label free technologies such as interferometry (Octet) or surface plasmon resonance (Biacore, Carterra)
o Direct experience with independent acquisition of kinetics and affinity characterization datasets.
o Detailed experience in data analysis and reporting in kinetics and affinity measurements.
o Capable at optimizing high-throughput protocols.
o Solid experience with protein biochemical analysis, including assay development (eg. ELISA and ECLIA, etc) and protein quality control characterizations.
● Strong collaborative, organizational, and presentation skills
● Ability to design and improve upon advanced protocols and procedures
● Ability to direct Research Associates, Technicians and CRO’s
● Ability to document, maintain, and share an organized account of lab work and results
Preferred qualifications:
● 2+ years post PhD experience
● Understanding in immunology research and industrial biologics R&D
● Mentoring and managing experience
We are an Equal Opportunity employer committed to a diverse workforce. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability.
Applicants please send an email to careers@seismictx.com, including a resume and a short self-introduction.
Sorry for the off topic post. If anyone is looking for a job around Boston area in US, please check the link below.
www.linkedin.com/jobs/view/2662640332/?r...RPGWslMQWMgEOQ%3D%3D
Who we are
Seismic Therapeutic is a VC-backed biotechnology startup focused on the intersection of structure, protein engineering, machine learning and immunology founded by Tim Springer, Jeff Ravetch, Debora Marks and Alan Crane.
What we offer you
As a member of our new and quickly growing company, you’ll help us shape Seismic from the very beginning into a startup that not only takes its scientific mission seriously but also provides a positive and supportive workplace environment and culture. Seismic will have the opportunity to benefit from the insight, diversity, and talent that you’ll bring. Together, we’ll help bring therapeutics to the patients who need them most.
Our mission
Seismic is determined to help patients in need, starting with novel approaches to protein engineering, machine learning and immunology, and ending with clinic-ready drugs. At our core, our focus is on phenomenal science, meritocracy, a superstar team, supportive culture, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality – all we need is you! Success will enable treatment for millions of patients with currently incurable, often disabling and deadly diseases, and we invite you to become a part of that.
Where?
Seismic is located in the dynamic biotech community in Watertown, alongside other new companies that are turning ideas into reality and changing the biotech and medical scenes for the better. We are thrilled to expand our Team with hardworking, highly qualified, highly motivated individuals to join us in our lab space.
Available position
Scientist/Senior Scientist, Biochemistry and protein interactions
General role: In coordination with scientific leadership, you would play a central role in designing and implementing Seismic’s pipeline, with particular focus on processes occurring during biotherapeutic candidate generation, screening and analysis. This role will involve exploring customized solutions in the field of protein-protein interactions, followed by detailed qualitative and quantitative sample analysis, leading into high-throughput screening and characterization techniques. Successfully meeting these challenges will require not only a broad range of protein biochemistry skills, independent thinking, and an aptitude for troubleshooting, but also a strong, creative drive to develop new assays as the need arises.
Your work in this role would be in collaboration with scientists and computational experts throughout Seismic, learning and contributing to many aspects of our pipeline, including the iterative design and production of biotherapeutics. You would be responsible for understanding project goals and for creatively optimizing solutions to ensure their success. Over time you would take on additional responsibilities and contribute to new projects.
Responsibilities:
● Design and implement protocols for characterizing protein-protein interactions.
● Design and optimize qualitative and quantitative biophysical and biochemical studies of biotherapeutic molecules, including assay development and protein QC.
● Share recommendations and insight for pipeline improvement toward higher-throughput and efficiency
● Collaborate with a diverse team of wet-lab scientists, protein engineers, and computational scientists
● Maintain an in depth understanding of the biochemistry, molecular structure and wider role of each candidate through critical analysis of the literature.
Basic qualifications:
● PhD in chemistry, biology, biochemistry, biomedical engineering, or related field
● 5+ years hands-on wet lab experience, including at least two of the following:
o Strong expertise in characterizing protein-protein interaction using label free technologies such as interferometry (Octet) or surface plasmon resonance (Biacore, Carterra)
o Direct experience with independent acquisition of kinetics and affinity characterization datasets.
o Detailed experience in data analysis and reporting in kinetics and affinity measurements.
o Capable at optimizing high-throughput protocols.
o Solid experience with protein biochemical analysis, including assay development (eg. ELISA and ECLIA, etc) and protein quality control characterizations.
● Strong collaborative, organizational, and presentation skills
● Ability to design and improve upon advanced protocols and procedures
● Ability to direct Research Associates, Technicians and CRO’s
● Ability to document, maintain, and share an organized account of lab work and results
Preferred qualifications:
● 2+ years post PhD experience
● Understanding in immunology research and industrial biologics R&D
● Mentoring and managing experience
We are an Equal Opportunity employer committed to a diverse workforce. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability.
Applicants please send an email to careers@seismictx.com, including a resume and a short self-introduction.
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