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What Binding Kinetics Can Tell You That Affinity Can't.
- NMCCANN2
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8 years 6 months ago - 8 years 6 months ago #1
by NMCCANN2
What Binding Kinetics Can Tell You That Affinity Can't. was created by NMCCANN2
Hey Everyone!
As scientists, we often have to choose which binding affinity technique to use in order to characterize our interactions. The binding affinity is an important number, but it doesn’t tell the whole story. Binding kinetics and specificity are critical for understanding the biological system that is being studied, especially for applications such as drug discovery and understanding molecular disease mechanisms.
We created a piece dedicated on this particular topic of why we study binding kinetics and how it serves to provide the whole story rather than relying on binding affinity; the tip of the iceberg.
After reading the blog , let me know if you have any questions, and I will be more than happy to answer your questions. Also, feel free to comment on your own research experiences and what techniques you use to understand the biological system you’re studying.
Cheers.
As scientists, we often have to choose which binding affinity technique to use in order to characterize our interactions. The binding affinity is an important number, but it doesn’t tell the whole story. Binding kinetics and specificity are critical for understanding the biological system that is being studied, especially for applications such as drug discovery and understanding molecular disease mechanisms.
We created a piece dedicated on this particular topic of why we study binding kinetics and how it serves to provide the whole story rather than relying on binding affinity; the tip of the iceberg.
After reading the blog , let me know if you have any questions, and I will be more than happy to answer your questions. Also, feel free to comment on your own research experiences and what techniques you use to understand the biological system you’re studying.
Cheers.
Last edit: 8 years 6 months ago by NMCCANN2.
The following user(s) said Thank You: BrukerSPR
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- peter47
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8 years 1 month ago #2
by peter47
Replied by peter47 on topic What Binding Kinetics Can Tell You That Affinity Can't.
nice blog, having a great information, thanks for sharing!
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