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why thiol coupling won't work for oligonucleoti
- OldForum
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17 years 10 months ago #1
by OldForum
why thiol coupling won't work for oligonucleoti was created by OldForum
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Anybody knows why we can not immbolize oligonucleotide through thiol coupling method onto Biacore C1 sensor chip. Thanks for you reply.
Anybody knows why we can not immbolize oligonucleotide through thiol coupling method onto Biacore C1 sensor chip. Thanks for you reply.
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17 years 10 months ago #2
by OldForum
Replied by OldForum on topic Thiol immobilisation
Are you aware that peptides can give very low signals when immobilized? But you can also easily immobilize to much and mask any further binding!
May this publication can give anay help
1: J Mol Recognit. 2006 Jul-Aug;19(4):363-71. Links
Modular, self-assembling peptide linkers for stable and regenerable carbon nanotube biosensor interfaces.Contarino MR, Sergi M, Harrington AE, Lazareck A, Xu J, Chaiken I.
May this publication can give anay help
1: J Mol Recognit. 2006 Jul-Aug;19(4):363-71. Links
Modular, self-assembling peptide linkers for stable and regenerable carbon nanotube biosensor interfaces.Contarino MR, Sergi M, Harrington AE, Lazareck A, Xu J, Chaiken I.
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